Tag: Science
The clown doctor will see you now – and you’ll get better, quicker
September 9, 2024 Ellen Phiddian
(Back in the 80s I heard a story of Norman Cousins putting his apple juice in a specimen cup, then later taking a sip while listening to a visitor. I think of Norman Cousins when I see headlines like this one. I don’t believe he was a clown, but others’s mileage may vary, as to humor in the hospital, also Norman Cousins, not to mention clowns.)
Medical clowns are known to have a positive therapeutic impact on kids in hospitals for a range of health issues, and now it’s been shown they can reduce the length of stay and antibiotic use for children with pneumonia.
A study, done on 51 children, found that those visited by medical clowns on average left hospital more than a day earlier than those who weren’t.
“Medical clowns undergo specific training to work in hospitals,” says Dr Karin Yaacoby-Bianu, a researcher at the Carmel Medical Centre and Israel Institute of Technology, Israel.
“They have been shown to reduce pain and alleviate stress and anxiety in children and their families during medical treatment, and have been gradually integrated into many aspects of hospital care.
“But their impact on children being treated for pneumonia has not been investigated.”
Yaacoby-Bianu presented her team’s research at the 2024 European Respiratory Society Congress.
“Community acquired pneumonia is one of the leading causes of hospitalisation in children, globally,” she says.
The team split 51 children, aged between 2 and 18, who had been hospitalised with pneumonia, into 2 groups.
They all received standard care, but one group also had four 15-minute visits from a medical clown from the Dream Doctors Project during their stays.
The clowns did a variety of activities including music, singing, and guided imagination.
The group visited by clowns stayed in hospital for 43.5 hours on average, while the control group stayed in hospital for 70 hours on average.
Children visited by clowns needed an average of 2 days of IV antibiotic treatment, while the control group required 3. Other medical markers, like heart rate and inflammation, were lower in the clown group.
“While the practice of medical clowning is not a standardised interaction, we believe that it helps to alleviate stress and anxiety, improves psychological adjustment to the hospital environment and allows patients to better participate in treatment plans like adherence to oral antibiotics and fluids,” explains Yaacoby-Bianu.
“Laughter and humour may also have direct physiological benefits by lowering respiratory and heart rates, reducing air trapping, modulating hormones, and enhancing the immune function.”
Dr Stefan Unger, a paediatrician at the Royal Hospital for Children and Young People Edinburgh, UK, who wasn’t involved in the research, says the study shows the positive effect humour can have in healthcare. (snip-MORE)
https://cosmosmagazine.com/health/body-and-mind/medical-clowns-pneumonia/
How fast can a fruit fly walk – scientists built mini treadmills and found out
September 8, 2024 Evrim Yazgin
(I want to guess that it’s the same everywhere, and ask: did they put these treadmills on bananas?)
Fruit flies on treadmills are giving scientists insights into how insects walk in ways that previous, more invasive techniques could not.
Researchers want to understand how insects’ nervous systems respond to rapid changes underfoot. All animals must navigate potential hazards and changes in terrain, otherwise injury from falls would be likely (send this to your clumsy friend or relative).
Animals as diverse as flies, cockroaches, rats and humans all show similar ways of readjusting after a trip, for example.
Studying how insects adjust their walking will help scientists understand proprioception: how the body continually senses its articulation and movement.
These techniques have been helpful in evaluation and treatment of people, such as stroke patients, who have locomotive issues.
University of Washington researchers published in Current Biology their findings when fruit flies – Drosophila melanogaster – were put on specially-designed miniature treadmills.
Fruit flies are a good model for mapping neural locomotion control because they have a compact, fully mapped nervous system. Previous studies have also given scientists a suite of genetic tools to perform precise and specific manipulations of the fly’s nervous system.
Traditionally, researchers have studied insect locomotion either free walking or tethered.
Tethered insects have a small camera mounted on a stick attached to their backs. Unsurprisingly, this method is not the most comfortable for the insect, but an advantage of this approach is that it allows the fly’s movements on 3D surfaces to be studied.
“One disadvantage of studying locomotion in tethered flies is that their posture is constrained and normal ground reaction forces may be disrupted, which could affect walking kinematics,” the authors of the new study write.
Enter the Drosophila’s very own treadmill.
The researchers were able to track fly walking over long periods of time. Split-belt treadmills were used to investigate how the flies reacted to belts with different speeds on either side of the body.
Without the burden of a tethered camera, the flies were able to strut their stuff freely.
“At the extremes, flies on the treadmill were able to sustain walking at a max belt speed of 40 mm/s and surpassed an instantaneous walking velocity of 50 mm/s [about 0.18km/h], which is the fastest walking speed ever reported for Drosophila melanogaster,” the researchers say. (snip-MORE)
https://cosmosmagazine.com/science/biology/fruit-flies-insect-walking-treadmill/
Monkeys give each other names too
This is so cool!
September 4, 2024 Evrim Yazgin
Marmosets do something that only humans, dolphins and elephants have been known to do: give each other names.
“Phee-calls” – a specific vocal call – used to identify and communicate between individual marmosets are described in new research published in the journal Science. Listen:
https://players.brightcove.net/5483960636001/default_default/index.html?videoId=6361433757112
There are 22 species of marmoset native to South America and occasionally spotted in Central America. The generally live in small family groups of 2 to 8 individuals.
The common marmoset weighs just a few hundred grams and is about 19cm tall. They are easily recognised by their large, white ear tuffs.
Naming other individuals is a highly advanced cognitive skill in social animals. Interestingly, our closest evolutionary relatives, non-human primates, have until now appeared to lack this ability.
Researchers uncovered the phee-calls in marmosets by recording their conversations.
They found that, not only do the little monkeys use phee-calls to address specific individuals, they are also able to tell when a call was directed at them and responded more accurately when it was.
“This discovery highlights the complexity of social communication among marmosets,” explains study lead and senior author David Omer from the Hebrew University of Jerusalem. “These calls are not just used for self-localisation, as previously thought – marmosets use these specific calls to label and address specific individuals.”
The researchers also noticed marmosets within a family group used similar vocal labels to address different individuals. Adult marmosets were even able to learn the names of individuals they weren’t related to by blood.
Such vocalisations may help marmosets in dense rainforest habitats where visibility is limited.
Baby marmoset monkey named Bareket. Credit: David Omer’s Lab.
“Marmosets live in small monogamous family groups and take care of their young together, much like humans do,” says Omer. “These similarities suggest that they faced comparable evolutionary social challenges to our early pre-linguistic ancestors, which might have led them to develop similar communicating methods.”
Understanding how social communication developed in marmosets could help explain human language evolution.
In the Spring edition of Cosmos Magazine, Drew Rooke looks at the prospects of talking to whales, and Amalyah Hart looks at insect consciousness. Out September 26.
https://cosmosmagazine.com/nature/animals/marmoset-monkey-names/
3 for Science on Labor Day
so I guess you may read them tomorrow, if you like. 😎
Biologists have studied an extreme gymnast of the animal kingdom, watching as it moves so quickly it appears to all but vanish.
The globular springtail (Dicyrtomina minuta) is a small but mighty bug that can backflip more than 60 times higher and 100 times longer than its own body length.
This tiny bug grows to only a couple of millimetres and can’t sting, bite, or fly its way out of danger. Instead, its preferred method of avoiding predators is to flip out so forcefully it seems to disappear! (snip-More on the page, with photos)
Next, a possible source of new antibiotics (and this brought Ten Bears to my mind, for some reason):
A study has found promising antibiotic candidates inside bacteria harvested from the deep Arctic Sea.
The research, by Finnish and Norwegian researchers, is published in Frontiers in Microbiology.
Antibiotic discovery has slowed in recent decades, which has exacerbated the risks of antibiotic resistance.
Most licensed antibiotics – about 70% – have been derived from a type of soil-dwelling bacteria called actinobacteria.
“For example, members of the Streptomyces genus produce several secondary metabolites, including clinically useful antibiotics such as tetracyclines, aminoglycocides and macrolides,” says corresponding author Dr Päivi Tammela, a professor at the University of Helsinki, Finland.
But soil isn’t the only place these bacteria can be found.
“Marine actinobacteria found in the sea, on the seafloor, or within the microbiome of marine organisms, have received far less attention as possible sources of antibiotics,” says Tammela. (snip-More on the page)
Then, an analysis for coal phase-out in Asia:
Countries in the Asia-Pacific region account for 76% of the world’s thermal coal power generation, and many of these plants will need to retire early to meet global emissions targets.
But according to a new analysis, it’s possible to phase these coal plants out and transition to renewable energy while investors still make money.
The study, done by Australian, Singaporean and Chinese researchers, is published in Energy Policy.
“There is a drive and interest from a number of different investors like the Asian Development Bank, but also private sector investors, to finance the early retirement coal fired power plants,” lead author Professor Christoph Nedopil Wang, director of Griffith University’s Asia Institute, tells Cosmos.
Nedopil and colleagues looked specifically at 6 Chinese-sponsored coal-fired power plants in Vietnam and Pakistan.
“With investors wanting to invest in, and ideally also providing lower cost financing for, green projects, refinancing of these coal fired power plants becomes possible at a lower cost,” says Nedopil.
The researchers modelled the future performance of these stations under a variety of financing and geoeconomic scenarios.
“That brought us to the conclusion that, depending on the age of the coal-fired power plant, we can retire these plants earlier than currently envisaged, while reducing the financing cost and therefore increasing enterprise value,” says Nedopil. (snip-More on the page)
Science on Tuesday
Chalk-coated fabrics could make clothes even cooler
August 26, 2024 Ellen Phiddian
US researchers have developed a chalk-based coating that can reduce the temperature under fabric by roughly 5°C.
The researchers say their environmentally benign substance could be used to coat any type of fabric and turn it into a radiative cooling textile.
“We see a true cooling effect,” says Evan Patamia, a graduate student at the University of Massachusetts Amherst.
“What is underneath the sample feels colder than standing in the shade.”
Patamia presented the team’s invention at the American Chemical Society’s 2024 Fall Meeting earlier this week.
Substances that can both reflect sunlight, and allow body heat to escape, are well-known to chemists. But they generally require costly or environmentally dangerous materials to make.
“Can we develop a textile coating that does the same thing using natural or environmentally benign materials?” summarises chemist Trisha Andrew, also at Amherst, of the work done by her and her colleagues.
Inspired by crushed limestone, which is used to cool buildings, the researchers tried solutions of calcium carbonate – the main component in limestone and chalk – as well as barium sulphate.
They used squares of fabric treated with a process called chemical vapour deposition, which added a layer of a carbon-based polymer onto the textiles.
When dipped in the solutions, the fabrics built up a chalky matte layer of crystals which could reflect UV and infrared light.
They tested the treated fabrics outside on a warm afternoon, and air underneath them was about 5°C cooler than the ambient temperature, and roughly 9°C cooler than air under untreated fabrics.
The coating is also resistant to laundry detergents.
“What makes our technique unique is that we can do this on nearly any commercially available fabric and turn it into something that can keep people cool,” says Patamia.
“Without any power input, we’re able to reduce how hot a person feels, which could be a valuable resource where people are struggling to stay cool in extremely hot environments.”
Andrew is now part of a startup aiming to test the process on larger bolts of fabric, to see if it can be scaled to industry.
https://cosmosmagazine.com/science/chemistry/chalk-coating-fabric-cool/
Two for science on Monday!
Jelly plays Pong and gets better at with practice
August 25, 2024 Imma Perfetto
A hydrogel has learned to play the 1970s video game “Pong” and improved its ability to hit the ball by 10% with some practice.
Dr Hayashi, a biomedical engineer at the University of Reading in the UK, says: “Our research shows that even very simple materials can exhibit complex, adaptive behaviours typically associated with living systems or sophisticated AI.
“This opens up exciting possibilities for developing new types of ‘smart’ materials that can learn and adapt to their environment.”
The research is described in a paper published in Cell Reports Physical Science.
Video link, an example run of a hydrogel playing Pong.
https://players.brightcove.net/5483960636001/HJH3i8Guf_default/index.html?videoId=6360855643112
Credit: Cell Reports Physical Science/Strong et al.
What is a hydrogel?
A hydrogel, like gelatine or agar, is made of a 3D network of polymers that become jelly-like when water is added.
The hydrogel in this study is an “ionic electro-active polymer”, where the media surrounding the polymer matrix contains charged particles, in this case hydrogen ions.
As a result, it can deform when an electric current is applied to it.
Stimulation by an electric field causes the hydrogen ions migrate and, as they move, drag water molecules with them, causing areas to swell.
“The rate at which the hydrogel de-swells takes much longer than the time it takes for it to swell in the first place, meaning that the ions’ next motion is influenced by its previous motion, which is sort of like memory occurring,” says first author and University of Reading robotics engineer, Dr Vincent Strong.
“The continued rearrangement of ions within the hydrogel is based on previous rearrangements within the hydrogel, continuing back to when it was first made and had a homogeneous distribution of ions.”
It’s this property the researchers exploited to teach the hydrogel to play Pong.
How does a hydrogel play Pong? (snip-More on the page)
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Balloon carrying telescope at poles to spot exoplanets: get EXCITEd
August 23, 2024 Ellen Phiddian
NASA is about to launch a helium balloon carrying a telescope, to test its ability to see exoplanet atmospheres.
The Exoplanet Climate Infrared Telescope (EXCITE) is eventually destined to fly around the poles, collecting data above much of the Earth’s atmosphere, but its first test flight is due to happen from the USA in the next few months.
It will be launched for the first time from the Columbia Scientific Ballooning Facility in New Mexico.
“EXCITE can give us a three-dimensional picture of a planet’s atmosphere and temperature by collecting data the whole time the world orbits its star,” says principal investigator Peter Nagler, from NASA’s Goddard Space Flight Center. (snip-More on the page)
First accurate simulation of a supermassive black hole destroying a star
(And of course you should listen to “Supermassive Black Hole” by Muse while enjoying this article. It’s the real only way. 😉)
August 21, 2024 Evrim Yazgin
Astrophysicists at Melbourne’s Monash University have generated the first simulation which accurately depicts what happens when a star ventures too close to a supermassive black hole.
The research, published in Astrophysical Journal Letters, is a technical milestone in our attempts to understand these mysterious cosmic giants.
Video on the page, or here on YouTube.
First author Daniel Price, a professor at Monash, tells Cosmos that there are about 100 events which have been observed over the past decade-and-a-half which astronomers believe fit the bill to be a star being destroyed by a supermassive black hole, also called a tidal disruption event (TDE).
Not X-ray vision
But these observations have thrown up some odd measurements which haven’t been explained until now.
“If you dump a bunch of material close to black hole and form an accretion disk around that black hole, there’s a prediction for where the material should land,” Price says. “The material at that location should be more than a million degrees in temperature. It should generate X-rays.
“So, if you have unobscured stuff feeding a black hole, you get X-ray emission. For example, the black hole sources in the galaxy, they’re all X-ray emitters.”
Stars falling into supermassive black holes, however, do not result in emission of X-rays. They emit light in the visible, or optical, spectrum.
Current theories can only speculate why such events lead to material being flung toward us at 20,000km per second – about one-fifteenth the speed of light.
An eating analogy – but not in the way you think
Price explains that the simulation illuminates why it is optical light, not X-rays, which we observe when our telescopes pick up stars falling into supermassive black holes.
“The analogy with me eating is that you don’t see my stomach. You’re not seeing the thing that’s generating the energy, you’re seeing it reprocessed through my skin,” Price says. “If you look at my light curve, you see that I’m a constant temperature of 38°C all day.
“My light curve is very much like a disruption event. The temperatures are pretty much constant. Luminosity changes a bit, but you infer that’s because the size of the objects changing, but the temperature evolution is very flat. So, it looks like exactly like me, just a lot warmer and a lot bigger.”
In fact, this size of the photosphere – the object which emits the optical rays – itself is surprising, says Price.
The photosphere in the simulation, which matches observations, is about 100 astronomical units (AU), where 1 AU is the distance from the Earth to the Sun (roughly 150 million kilometres).
Video on the page, or here on YouTube
“No one knows what it is,” Price laughs.
What we see is muffled
Price says the simulations confirm a theoretical explanation for these unexpected observations called the Eddington envelope.
“That’s the concept that you’re stuffing material down towards the black hole faster than it can process it,” Price says. “By process, I mean like the sun processes the energy from its core – it just kind of gently radiates it away. So the black hole can’t radiate away the stuff that you’re trying to feed it. And, so, it has to literally blow it away.”
This material “smothers” the black hole, absorbing the X-rays that the black hole emits and re-emitting it as optical light.
Price extends the eating analogy to an unpleasant place.
“Basically, it’s like stuffing your stomach. You’re going to vomit eventually. That’s pretty much what happens.”
The power of a simulation
“That’s the exciting thing in simulations. People have speculated for a long time and drawn illustrations and this kind of thing, but there’s no physics in that. That’s just what we call phenomenology. That’s how it must be to explain this phenomena. But we don’t know what produces that kind of envelope or layer, or reprocessing layer,” Price says.
The simulation, Price says, just requires the initial conditions – the star – the fluid mechanics governing the star, and the rules of general relativity.
“Then it’s just a technical challenge,” he says.
“In a lot of simulation work, you’re kind of guessing what might have happened,” he adds. “But in this case, we’re pretty sure what happens. It’s really nice to get that connection to the observations of transients from just chucking a star at a computer.”
Price explains that the simulation will set astrophysicists and astronomers up to be able to understand such phenomena much better as more observations are expected to be made soon.
“The first optical transient was only detected in 2010, but what’s coming is the Rubins observatory being built in Chile. That’s expected to boost the population of these things into the thousands.
“Having a good theoretical understanding of what the kind of phenomena is sets us up really well for that future flood of observations. It’s not just some theoretical speculation. There’s really something we can go after and understand by looking at it.”
News for people who pay attention to storms
Hailstone library improves predictions of damaging storms
August 19, 2024 Imma Perfetto
Scientists have compiled a library of hailstones to help fine-tune hailstorm simulations and make weather forecasts more accurate.
To make calculations more simple, conventional scientific hailstorm modelling assumes all hailstones are perfectly spherical. In reality, they’re a little more complicated than that.
“Hail can be all sorts of weird shapes, from oblong to a flat disc or have spikes coming out – no two pieces of hail are the same,” says Dr Joshua Soderholm, honorary senior research fellow at University of Queensland and research scientist at the Bureau of Meteorology in Australia.
In their new study in the Journal of the Atmospheric Sciences, Soderholm and collaborators explored whether compiling a reference library of non-spherical, natural hail shapes could change the outcomes of hailstorm modelling.
“Our study used data from 217 hail samples, which were 3-D scanned and then sliced in half, to tell us more about how the hailstone formed,” says Soderholm.
“This is effectively a dataset to represent the many and varied shapes of hailstones.”
According to lead researcher Yuzhu Lin, a PhD candidate at Pennsylvania State University in the US, the differences were dramatic.
“Modelling of the more naturally shaped hail showed it took different pathways through the storm, experienced different growth and landed in different places,” she says.
“It also affected the speed and impact the hail had on the ground. This way of modelling had never been done before, so it’s exciting science.”
While the modelling is currently only used by scientists studying storms, Soderholm says the end game is to be able to predict how big hail will be and where it will fall in real-time.
“More accurate forecasts would of course warn the public so they can stay safe during hailstorms and mitigate damage,” he says.
“But it could also significantly benefit industries such as insurance, agriculture and solar farming which are all sensitive to hail.”
Uterus transplant trial ends with bundles of joy
August 18, 2024 Ellen Phiddian
https://cosmosmagazine.com/health/medicine/uterus-transplant-trial-dallas/
(This piqued my interest for a number of reasons. It also made me think of Sen. Vance, very briefly. But it is news-y.)
A US study of 20 people who received uterus transplants has found the process feasible, with 14 recipients going on to have live births.
Researchers said there were no abnormalities in the children born via transplanted uterus, but they highlight risks from surgery that affected both recipients and donors.
The study, which is published in the Journal of the American Medical Association, reports on a clinical trial run at the Baylor University Medical Center in Dallas, USA.
Since the first successful uterus transplant in 2011, there have been about 100 transplants worldwide, from both living and deceased donors.
Recipients are generally women with “absolute uterine infertility” – that is, problems with their uterus that make them unable to have a successful pregnancy.
In the USA, there have been 48 uterus transplants since they began in 2016, with 33 of the recipients going on to have live births.
In this trial, researchers enrolled 20 people, aged between 20-36 years old, all of whom had absolute uterine infertility but at least 1 working ovary.
Participants received uterus transplants from 18 living and 2 deceased donors between 2016 and 2019.
Of the 20 participants, 6 had graft failures within a fortnight and lost the transplanted organ.
“During the study period, the technical success of graft survival improved with time and experience,” write the researchers in their paper.
All 14 of the successful transplant recipients went on to become pregnant via IVF, and give birth via caesarean.
Two of the recipients gave birth twice, resulting in 16 total live births. Some of the recipients had miscarriages, mostly early in their pregnancy, as well as having full-term pregnancies.
None of the 16 babies had congenital abnormalities, and none show any notable developmental delays to date (the oldest child the researchers have followed up with is 6). One child was diagnosed with autism at age 2 after missing communication milestones, and the researchers note his younger sister shows no signs of developmental delays.
Transplanted uteruses are typically removed again after 1 or 2 successful pregnancies, and this is the case with these 14 recipients. At the moment, 13 have had hysterectomies, while 1 still has the transplanted uterus in place for a second pregnancy.
Some of the surgeries in the trial – transplant donation, transplant reception, caesarean section, and graft hysterectomy – had complications.
Four of the living uterus donors had grade 3 complications – that is, they required surgery to fix – but none of them had experienced any long-term illness when they were followed up roughly 4 years later.
None of the successful graft recipients had severe complications from their transplant surgery, and while graft loss is a grade 3 complication, none of the 6 unsuccessful recipients had experienced long-term effects when they were followed up.
The researchers also point out that all recipients needed immunosuppression treatment to accept the donated organs, and the “long-term impact of immunosuppression in these otherwise healthy women remains unknown”.
In their paper, the researchers conclude that uterus transplants are technically feasible, but the surgeries involved carry risks for donors and recipients.
“The live birth success rate in this study suggests that a successfully transplanted uterus is capable of functioning at least on par with a native, in situ uterus,” they write.
But they also point out that the “currently prohibitive cost of uterus transplant” makes it difficult to tell how generalisable their results are.
Scottie's Playtime 