2 For Science, on Monday

Each of these struck my fancy, so I’m sharing.

Could we hit the “pause button” on human embryo development?

September 27, 2024 Imma Perfetto

The mechanisms that allow some mammals to pause the development of their young inside the womb also seem work in human cells, according to a fascinating new study published in the journal Cell.

Biologists discovered they could induce a dormant state in human cells by decreasing the activity of the mTOR signaling pathway, which they previously showed is a major regulator of this process in mice.

They triggered this dormant state not in human embryos, but in human pluripotent stem cells and stem-cell based models known as blastoids, which mimic the blastocyst stage of embryonic development at about 5 days post-fertilisation. (snip)

Until now it was unclear whether diapause could be triggered in humans.

“The mTOR pathway is a major regulator of growth and developmental progression in mouse embryos,” says co-senior author Aydan Bulut-Karslioglu of the Max Planck Institute for Molecular Genetics in Germany.

“When we treated human stem cells and blastoids with an mTOR inhibitor we observed a developmental delay, which means that human cells can deploy the molecular machinery to elicit a diapause-like response.”  

Cells in this dormant state show reduced cell division, slower development and a decreased ability to attach to the uterine lining. The ability to enter this dormant stage seems to be restricted to the blastocyst stage of development. (snip-MORE)

Explosive energy-dense material made from air (with plasma)

September 29, 2024 Ellen Phiddian

Chemists have made an extremely energy-dense, environmentally friendly fuel out of nitrogen.

They’ve done it by employing one of chemistry’s favourite hobbies, bullying nitrogen n (N2) into weird structures. An explosion occurred, but it was a small one.

The Chinese team has successfully made the element adopt a diamond-like structure, called cubic gauche nitrogen (cg-N) and importantly made it without extremely high pressures. In fact, they managed it at standard atmospheric pressure.

They’ve published their triumph in Science Advances.

Pure nitrogen-based molecules have drawn interest from chemists because they can release a tremendous amount of energy when they decompose. (snip-MORE)

Peace & Justice History for 9/30

September 30, 1962
Hundreds of Ku Klux Klan members, white students and others, tried to keep a black student, James Meredith, 29, from attending classes at the University of Mississippi in Oxford. They were supported by the governor, Ross Barnett, who had explicitly resisted the order of the Federal Circuit Court.In spite of the efforts to block his court-ordered registration, a deal to allow Meredith to register was reached between U.S. Attorney General Robert Kennedy and Governor Barnett. Meredith was secretly escorted onto campus; deputy U.S. marshals, border patrolmen and federal prison guards were stationed on and around the campus to protect him. Those standing guard were assaulted throughout the night with guns, bricks, Molotov cocktails, and bottles.


James Meredith being escorted to his classes
by U.S.marshals and the military.
Tear gas was used to try and control the crowd. Federal troops arrived, bringing the total to 12,000 (President Kennedy had activated soldiers and national guardsmen totaling 30,000), and the mob finally retreated. In the end, two were dead, 160 U.S. Marshals were injured (28 shot), 200 others injured, and 300 arrested.
Integrating Ole Miss  
JFK Library
September 30, 2003
The FBI began a criminal investigation into whether White House officials had illegally leaked the identity of an undercover CIA officer, Valerie Plame, wife of diplomat Joseph C. Wilson, IV. In early 2002 the CIA had sent Wilson to look into the claim that Saddam Hussein had sought to acquire yellow-cake uranium from the African country of Niger. Ambassador Wilson found nothing to support the claim, and some of the documents cited as evidence for the claim were clearly shown to be forgeries.
President Bush, nonetheless, repeated the claim in his January, 2003, State of the Union address as part of his argument for war in Iraq.
Wilson wrote a column in the New York Times in July, 2003, entitled “What I Didn’t Find in Africa.”

 
 Columnist Robert Novak a few days later published Plame’s identity following conversation with Deputy Secretary of State Richard Armitage. Plame, who previously had worked on counter-proliferation, was in charge of operations for the CIA’s Joint Task Force on Iraq, formed the summer before 9/11.
September 30, 2004
The U.S. Navy announce the shutdown of Project ELF.
read more

https://www.peacebuttons.info/E-News/peacehistoryseptember.htm#september30

Trump preps catalog of “cheating” claims for potential election loss

https://www.axios.com/2024/09/29/trump-voter-fraud-2024-election

Illustration of a voting booth with a siren on top.

Illustration: Allie Carl/Axios

Through public remarks, Truth Social screeds and more than 100 preemptive lawsuits, Donald Trump is assembling a detailed catalog of excuses for rejecting the results of the 2024 election — if he loses.

Why it matters: The Trump-aligned efforts to overturn the 2020 election — both overtly and covertly, peacefully then violently — shocked the American public. No one should be surprised this time around.

Listen to Trump: The former president, who risks jail time and more criminal trials if he loses, has expanded his range of baseless attacks on U.S. voting procedures in recent weeks and months.

  • Overseas voting: Trump falsely claimed Monday that Democrats are exploiting an overseas ballot program for expats and military members in order to circumvent “any citizenship check or verification of identity.”
  • Early voting: At a rally in Pennsylvania last week, Trump denounced what he called the “stupid” concept of voting 45 days before the election — floating conspiracy theories about his loss in the crucial swing state four years ago.
  • Mail-in voting: Trump has long despised mail-in ballots. He’s recently attacked the U.S. Postal Service as incompetent and untrustworthy — even as the GOP has pushed its voters to embrace the practice.

Zoom in: The millions of undocumented migrants who have crossed into the U.S. during the Biden administration are a top campaign issue. They’re also being used to fuel new voter fraud conspiracy theories.

  • Earlier this month, Trump demanded that House Republicans use the threat of a government shutdown to pass a measure requiring proof of citizenship to register to vote in federal elections.
  • That effort failed, but it gave Trump and Republicans a new excuse to claim election fraud — even though it’s already illegal and exceedingly rare for non-citizens to vote in U.S. elections.

Between the lines: Even without evidence of voting irregularities, Trump is preparing to deploy broader rhetorical arguments for why the election was fundamentally unfair.

  • The former president has accused Democrats of “cheating” by swapping out President Biden for Vice President Kamala Harris in June, and engaging in “lawfare” through criminal prosecution.
  • “If there was no cheating — if God came down from on high and said ‘I’m going to be your vote tabulator for this election,’ I would leave this podium right now,” Trump said Sunday at a rally in Pennsylvania.
  • “We have to have a landslide because they cheat so damn much.”
 

The big picture: Since 2020, the Republican Party apparatus has been reorganized — from the top down — to give credence to Trump’s false claims that election fraud is a scourge on American politics.

  • Trump’s campaign and the Republican National Committee say they’ve built a network of about 175,000 volunteer poll watchers and poll workers, part of a relentless focus on “election integrity.”
  • In Georgia, a hard-right election board has passed new rules that Democrats fear could be used to undermine confidence in the results if Trump loses the critical battleground state.
  • House Speaker Mike Johnson (R-La.) drew outrage last week by pledging to certify the 2024 election and “follow the Constitution” only if it’s a “free, fair and safe election.”

What to watch: On Nov. 1, 2020, Axios reported that Trump had privately told confidants he planned to prematurely declare victory on election night if it looked like he was “ahead.”

  • That’s exactly what he did.
  • Given the likelihood that the election once again will take days to call, don’t be surprised to see the former president dust off that same playbook.

This is the Republican Party of tRump. Gang thugs

 Braddock had fled to the Philippines where he was eventually deported last year as an illegal alien and arrested in Los Angeles.

Earlier this week she launched a fugly $600 “vote freedom” necklace. Because people can hardly feed their families.

“It has been determined that Google has illegally used a system of only revealing and displaying bad stories about Donald J. Trump, some made up for this purpose while, at the same time, only revealing good stories about Comrade Kamala Harris.

Trump, as always, is lying. Financial disclosure records show that Paul Pelosi sold 2000 shares of Visa nearly three months ago. The DOJ filed its antitrust suit against Visa on Wednesday.

Yesterday the Hollywood Reporter interviewed luxury watch experts who declared that the “Swiss” watches are likely cheap crap made in China. A disclaimer on Trump’s website says that the watches sold may not look like the “representations” seen on the site. The disclaimer also pointedly make no promises about delivery.

“And yet she’s taken in the worst of those people. The killers, the jailbirds, all of the worst of the people. She’s taking them in. And then I have to sit there and listen to her bullshit last night.

A spokesperson for the Department of Homeland Security, which oversees ICE, said in a Saturday email: “The data in this letter is being misinterpreted. The data goes back decades; it includes individuals who entered the country over the past 40 years or more, the vast majority of whose custody determination was made long before this Administration. It also includes many who are under the jurisdiction or currently incarcerated by federal, state or local law enforcement partners.”

As Dale goes on to note, Trump’s lies have been widely spread by right wing media and GOP lawmakers, such as the Hitler-quoting GOP rep seen below.

Didn’t Have To Be This Way …

I want to thank Ten Bears for this video.  I really enjoy history and how it still affects us today.  I almost lost the link of his to reblog it as I switch videos to the secondary computer and keep reading and responding on the primary as I watch.    I am glad I found the original post as it saved me a lot of work.  All I can say is if you are interested in history, electric cars, and why we went to using gas when it was much cheaper and not totally profit driven, please watch this video.  Hugs.  Scottie. 

Anti-Trans Campaigner Outed As Having Forged Evidence – WPATH Files

I love Ethel’s videos and I have learned a lot about trans people from her.  She often does videos with herself in them but also sometimes does them with the drawn figures.   She has been very open with her transitioning journey, and I have followed her since she was a teen before she transitioned.   Her videos are remarkable for the detail and receipts she brings to them.   She does a lot of research, especially on trans women in sports issues.  She documents everything for the viewers to check in the about section and encourages fact checking her. 

In this video she sets up the fact that the anti-trans activist that falsely made claims about the WPATH files has a history of lying to try to push their issues.  I love watching her videos and if you are interested in trans issues and ways to debunk what the trans haters say, she is worth looking at her back work.   Her take down of the entire WPATH Cass report was wonderful and showed how totally false and misleading the report was.  The Cass report has now been totally debunked now in part to Ethel’s work.  Hugs.  Scottie

Today’s video returns to the #WPATHFiles which alleged malpractice by medical institutions who support the scientific legitimacy of gender affirming care, exposing the Files’ fatal flaws and its publisher’s sordid history of forging evidence. Hi, welcome to Essence of Thought with me, Ethel Thurston, as your host.

I had to!

Free Range by Bill Whitehead for September 29, 2024

Free Range Comic Strip for September 29, 2024

https://www.gocomics.com/freerange/2024/09/29

Live From New York!

Information we could all use.

A Bala Cynwyd woman got a fake letter notifying her she’d have to house migrants under a nonexistent Biden-Harris program

https://www.inquirer.com/politics/election/fake-letters-pennsylvania-voters-immigration-housing-20240927.html

The republican’s know their policies and ideas are very, very unpopular.   They can’t win on them, so they are forced to cheat and drum up fake fears to scare voters to vote for them.  Hugs.  Scottie


 

‘Congratulations’ the fake letter reads, ‘you have been selected as a Wayward Steward exchange home for homeless immigrants and victims of foreign wars.’

A Bala Cynwyd couple received a fraudulent letter from the Pennsylvania Congressional Office of Immigration Affairs this week informing her that she'd been selected as a "wayward steward" to house five refugees. The office does not exist, nor does the program. Elizabeth Bennett holds the letter on Sept. 27, 2024.
A Bala Cynwyd couple received a fraudulent letter from the Pennsylvania Congressional Office of Immigration Affairs this week informing her that she’d been selected as a “wayward steward” to house five refugees. The office does not exist, nor does the program. Elizabeth Bennett holds the letter on Sept. 27, 2024.Read moreCharles Fox / Staff Photographer
 

A Bala Cynwyd voter got a detailed letter this week from the made-up Pennsylvania Congressional Office of Immigration Affairs notifying her that her household had been selected to house five migrant refugees.

No office exists, nor does such a government-mandated housing program, but the letter, doctored to look like an official government document, provided specific details designed to mislead someone less attuned to a scam — and laid the blame for the fake program at the feet of President Joe Biden and Vice President Kamala Harris during a heated and close election in which immigration has increasingly become a focal point.

“I’m concerned to find out how many people might have actually gotten it and to make sure the record’s set straight so people aren’t getting fearful or angry and deciding to vote another way,” Elizabeth Bennett, 62, said.

The letter says Bennett was selected as a “wayward steward” as part of “US5Ca12-B … written into Law by President Joe Biden and Vice President Kamala Harris.” No such law exists.

 

It advised Bennett she’d been selected based on property and income records and would receive an $80 weekly stipend for food costs. The letter suggested a “minimum of one bedroom be prepared with a minimum of 5 beds,” with a link to “government-approved” bunk beds.

The return address listed is for an intersection in front of the Capitol building in Harrisburg.

Neither the governor’s office nor the department of state immediately returned a request for comment.

Bennett is unsure why she was targeted. She has a large Harris/Walz sign in her front yard. Ironically, she’s also done volunteer resettlement work with immigrants for the last 30 years but she assumes that was just a coincidence.

 

“Of all the people they could send this to, I would be the one who is like, ‘OK let’s get the room set up, we gotta take care of these people,’” she said. But as she read on, she realized the program was fake and intended to scare people.

“I could definitely see, even for me reading this letter it felt threatening even though I’m very pro-immigrant because it felt like something that was being imposed on me,” she said.

It’s unclear if other Pennsylvanians received the letter. Bennett posted about it in small Facebook groups but hasn’t heard from others who received it.

But whoever created the letter took time to make it look like an official document, including an imprint of a fake Pennsylvania seal on the letterhead and a stamped date informing Bennett when to expect the migrants.

 

A listed phone number for the fake office, with a Harrisburg area code, goes to a voicemail for the named office where a messaging service invites the caller to press one for housing vouchers, two for reimbursements, and three to “expand your footprint to help more people.”

The letter Bennett received went on to specify garages or sheds without electricity and running water could not be used.

“Thank you for your dedication to the health and safety of these future Americans!” it concluded.

Misinformation about migrant resettlement and illegal immigration has been rampant in the campaign. Former President Donald Trump and his running mate JD Vance have made it a focus of their bid for the White House claiming that migrant resettlement has drained resources from small towns and that illegal immigration has driven crime and economic hardship, with little evidence.

 

The federal Office of Refugee Resettlement does invite people to be part of a government hosting program but participation is entirely optional.

State Rep. Joe Hohenstein (D., Philadelphia) is an immigration attorney who called the letter “a betrayal of the actual spirit of our country.”

“It’s definitely designed to make people think that there’s a broader government program to resettle refugees and my guess is that the intention is to stir up fear of immigrants and refugees,” he said. “That’s reprehensible It’s a betrayal of the actual spirit of our country of being a welcoming beacon to people who are seeking freedom.”

In the next week, Hohenstein is cosponsoring a bill to establish an Office of New Pennsylvanians, which would help provide support services for refugee businesses and migrants fleeing persecution in Pennsylvania.

“This would provide help to people who need it,” he said. “It would not be a mandate to anyone.”

Julia Terruso
I cover politics and our divided electorate. I’m interested in what unites and separates us, shifts in voting trends, and grassroots movements.