Hibernating For Better Health?

Unlocking the genetic ‘control switches’ of hibernation

Velentina Boulter – Velentina Boulter is science journalist based in Melbourne.

A small brown mouse curled up asleep in its nest
Common dormouse. Credit: Michel VIARD/Getty Images

New research has identified specific regions of DNA that regulate hibernation by tweaking metabolism. The findings could offer pathways to new treatments for metabolic disorders like type 2 diabetes in humans.

When hibernating animals wake, they reverse dangerous health changes similar to those seen in type 2 diabetes, muscle atrophy, Alzheimer’s disease and stroke. Researchers hope that unlocking hibernation regions in the human genome could help develop treatments for these potentially fatal health conditions.

“If we could regulate our genes a bit more like hibernators, maybe we could overcome type 2 diabetes the same way that a hibernator returns from hibernation back to a normal metabolic state,” says Elliot Ferris, a bioinformatician at the University of Utah (U of U) Health in the US.

Ferris is co-author of 2 new studies which pinpointed that DNA regions near a gene cluster called the “fat mass and obesity (FTO) locus” play a crucial role in the ability to hibernate. While the FTO locus also appears in humans, hibernating animals use it in a different, and potentially more advantageous way.

“What’s striking about this [FTO] region is that it is the strongest genetic risk factor for human obesity,” says senior author of the study, Chris Gregg, a professor in neurobiology at U of U Health.

According to the World Health Organization, 1 in 8 people worldwide were living with obesity in 2022. Obesity can lead to an increased risk of type 2 diabetes, heart disease and other health implications, which illustrates the importance of preventing and treating the condition.

“Humans already have the genetic framework,” says Susan Steinwand, a research scientist at U of U and co-author of the studies. “We just need to identify the control switches for these hibernator traits.”

To locate the hibernation-specific regions of the genome, the team used multiple independent whole-genome technologies to compare mammals that do and don’t hibernate.

“If a region doesn’t change much from species to species for over 100 million years but then changes rapidly and dramatically in 2 hibernating mammals, then we think it points us to something that is important for hibernation, specifically,” says Ferris.

The hibernator-specific DNA regions (located close to the FTO locus) weren’t genes but DNA sequences called “cisregulatory elements” (CREs) which contact nearby genes to either turn up or down their expression, almost like a film director coordinating cinematographers, set designers and actors. The researchers found the CREs regulated the activity of neighbouring genes, including those involved in metabolism.

When they mutated these regions in mice, the researchers observed changes in weight and metabolism. Some of the mutations the researchers performed sped up the weight gain, while others slowed it down. Other mutations affected the body’s ability to recover body temperature after hibernation.

They suggest that this is what allows animals to gain weight before entering hibernation and then slowly release the energy in their fat reserves during the winter.

This means that mutating a single hibernator-specific region has wide-ranging effects extending far beyond the FTO locus, says Steinwand.

“It’s pretty amazing,” she says. “When you knock out one of these elements – this one tiny, seemingly insignificant DNA region – the activity of hundreds of genes changes.”

The studies suggest that CREs might also play a role in regulating human metabolism.

While understanding this flexibility could lead to better treatments for disorders like type 2 diabetes, the study also helps indicate which DNA elements should be explored in future studies.

“There’s potentially an opportunity – by understanding these hibernation-linked mechanisms in the genome – to find strategies to intervene and help with age-related diseases,” says Gregg.

“If that’s hidden in the genome that we’ve already got, we could learn from hibernators to improve our own health.”

The research has been published in the journal Science.

Originally published by Cosmos as Unlocking the genetic ‘control switches’ of hibernation

Some Comics That Gave Me A Giggle This Morning

(I wait on news in favor of comics in the mornings on BP days.)

https://www.gocomics.com/bliss/2025/08/05

https://www.gocomics.com/broomhilda/2025/08/05

https://www.gocomics.com/calvinandhobbes/2025/08/05

https://www.gocomics.com/closetohome/2025/08/05

https://www.gocomics.com/darksideofthehorse/2025/08/05

https://www.gocomics.com/foxtrotclassics/2025/08/05

https://www.gocomics.com/jerry-king-comics/2025/08/05

Whistleblower: 10-year-old Palestinian boy ‘gunned down’ after receiving food aid

Former US Green Beret says Israel committed war crimes at Gaza food distribution site | BBC News

In Gaza, hunger forces impossible choices as Hamas releases propaganda video of hostage

Enjoy Your Morning Beverage, and See 25 Years Into The Future-

How The World Will Look Very Different in 2050, According to Neil deGrasse Tyson

Neil deGrasse Tyson says you’ll regrow organs and vacation in space by 2050 — lock in.

By Asheea Smith Published August 2, 2025

Leave it to Neil deGrasse Tyson to casually predict the next 25 years like it’s no biggie. During episode 1904 of the Joe Rogan Experience, the astrophysicist, author, and science celeb offered a bold glimpse into where humanity might be headed in the next 25 years. While flying cars didn’t make the cut (sad face), his projections are closely aligned with today’s advances in science and technology — and some could be closer than we might expect. 

So, who exactly is Tyson, and what does he think the world might look like by 2050? Get in — we’re going exploring.

Who is Neil deGrasse Tyson?

If you’ve ever caught the eye-watering space series, “Cosmos” or heard someone break down the mysteries of the universe without sounding like a textbook — you’ve probably heard of Tyson. Born in New York City, Tyson graduated from the Bronx High School of Science. He later earned his Bachelor of Arts in Physics from Harvard University in 1980 and went on to complete a Masters and Ph. D in Astrophysics from Columbia University in 1989 and 1991, per Britannica

Tyson is best known for hosting the celestial TV series, “Cosmos: A Spacetime Odyssey” and his radio program, “StarTalk.” Beyond his obsession with exploding stars, black holes, and dark matter, he gives viewers a grip on what the heck is going on in the cosmos, and what it has to do with us.

Now, for his next trick, Tyson’s turning that cosmic lens toward laying out what he believes is next for humanity.

Mental Illness Will Be Cured

(Photo by Eric Kayne/Getty Images)

“Neuroscience and our understanding of the human mind will become so advanced that mental illness will be cured, leaving psychologists and psychiatrists without jobs,” Tyson, 66, said during the interview.

The Take Over of Self-Driving Cars

(Photo by Mario Tama/Getty Images)

“Self-driving electric vehicles will fully replace all cars and trucks on the road. If you wanna be nostalgic with your fancy combustion engine sports car, you can drive on specially designed tracks,” Tyson explained.

Space Tourism

“The human space program will fully transition to a space industry, supported not by tax dollars, but by tourism,” Tyson said.

It seems that in Tyson’s vision, regular folks will be able to book a trip to orbit. Voyager Station — a space hotel set to open in 2027 — is already in the works, complete with a bar, restaurant, concert hall, gym, and a cinema theatre, per Astronomy.

The Cure for Cancer & Tailored Medicine

(Photo by Pablo Blazquez Dominguez/Getty Images)

“We develop a perfect ani-viral serum and cure cancer. Medicines will tailor to your own DNA, leaving no adverse side effects,” Tyson predicted to Rogan.

We’ll Regrow Limbs and Organs

(Photo by Leon Neal/Getty Images)

“We will learn how to regrow lost limbs and failing organs, bringing us up to the level of other regenerating animals on earth, like salamanders, starfish, and lobsters,” the “Cosmos” host stated.

Artificial Intelligence Won’t Become Our Overlords

(Photo by Spencer Platt/Getty Images)

“Instead of becoming our overlord and enslaving us all, artificial intelligence will be just another helpful feature of the tech infrastructures that serve our daily lives,” Tyson concluded.

Samuel L. Jackson!

Snagged it from Jeff Tiedrich’s Substack.

Snippet: here are your heroes of the day: the Swedish state-owned energy company Vattenfall, who hired Samuel L. Jackson to star in a commercial entitled “Motherfucking Wind Farms.”

enjoy.

And Now For Some Funny Fun

A Lime-Green Dildo Got Thrown Onto a WNBA Court. Chaos Ensued

Players cracked wise about the launched sex toy on social media.

By James Factora July 30, 2025

Lez Out July might be drawing to a close, but one WNBA fan made damn sure that it’s not going out without a bang, pun semi-intended. And by that, we mean that someone launched a lime- green dildo onto the court at an Atlanta Dream game last night.

The incident occurred during the fourth quarter of the Dream’s July 29 game against the Golden State Valkyries at the Gateway Center Arena in College Park, Georgia. With a minute left on the clock and both teams tied at 75 points, the drama was already high. Perhaps that’s why one attendee felt inspired to launch a dildo into the air and onto the court with truly impressive velocity.

(embedded tweet; I can’t get it, see it on the page, linked in headline)

At about 17 seconds into the above clip, you can see slowed-down footage of the dildo’s journey, seemingly tossed from somewhere high up in the stands and bouncing across the court into the sidelines. And yes, we did get a close-up shot of the “object” in question, as the commentators called it. Absolute Cinema, if you ask us.

(embedded tweet; I can’t get it, see it on the page)

Though the commentators said that there was “no room for that type of activity,” and we certainly don’t support launched objects at concerts and games, it seems that WNBA players themselves have at least enough room to make jokes about that type of activity online. Las Vegas Aces guard Kierstan Bell quote-posted a video of the incident with, “Damn how my shit get there,” and an eyebrow-raised emoji. Indiana Fever point guard Sydney Colson, meanwhile, posted, “Sorry I did NOT mean to throw that so far y’all.” Though she didn’t include a video, that lime-green heart emoji (which is weirdly close to the color of the actual dildo) makes this an unmistakable reference. (snip-good sports, all! MORE)

Health Dis/Misinfo That’s Dangerous For Young People

Opinion: Contraception Gives Young Women Control of Their Bodies—So Why Are So Many Girls Afraid to Use it?

Jul 28, 2025, 9:00am Shoshana Kaplan

One-third of young women who don’t take birth control say they fear its side effects. Misinformation plays a role, a health expert says.

This story is part of our monthly series, Campus Dispatch. Read the rest of the stories in the series here.

As long as contraception has been widely available, misconceptions about its safety—from weight gain fears to claims you need a birth control “cleanse” every few years—have scared some young women away from using it. Today, this kind of misinformation is no longer solely circulated in locker rooms or sleepovers. In the modern digital world, active misinformation and disinformation campaigns that deter people from using contraception circulate on social media—reaching millions.

The origin of this issue varies. Sometimes, rumors about birth control are intentionally created and promoted for political purposes; this is disinformation. Sometimes, false claims are unintentionally spread by people who believe their statements are true. Other times, one person misrepresents their real, lived experience as a universal truth.

The results are astonishing: A 2022 KFF study found that roughly one-third of reproductive-age women who are not on birth control cite fears of side effects as a reason for avoiding contraception.

Since the fall of Roe v. Wade in 2022, contraception and comprehensive sex education have become more than just public health priorities: They are now the front lines of defense in protecting reproductive rights and empowering people—young women especially—to make choices about their bodies.

I am a public health master’s candidate focused on reproductive health and communications. This summer, I am interning at the sexual health and equity non-profit Advocates for Youth, which champions bodily autonomy for young people. In my work here to develop sex education materials and resources for young people and educators, as well as in my academic research, I’ve come to believe that combatting digital misinformation about birth control will require a collective response.

Taking health advice from TikTok

It’s easy to see how young people can fall victim to digital misinformation: Imagine you’re a 15-year-old girl dealing with severe period pain, or perhaps your acne has gotten out of control. Or maybe, you’re just excited to start having sex for the first time and want to do so safely. After talking with your mom and doctor, you decide to try hormonal birth control. You feel relieved. After months of keeping this big life choice to yourself, you finally shared your needs—and you were heard. You have a plan.

That night, some two hours into your usual TikTok scroll, you’re shown a video featuring a beautiful young woman you recognize from your “For You” page. She says birth control not only wrecked her hormonal balance, but will also cause cancer. You’ve seen this creator’s lifestyle content before and always trusted her. In the most-liked comments, hundreds of people echo her experience, sharing stories of hair loss or feeling “crazy” on the pill. Some comment they’re grateful to have never started birth control at all. Nowhere in the comments do you see a doctor or other medical expert pushing back, insisting that birth control is safe and effective.

What do you do?

Perhaps you search TikTok for other perspectives. You find a couple videos from OB-GYNs disputing the claims. But the other creator’s post had more than 200,000 views and hundreds of comments, while that one OB-GYN’s explainer only has 5,000 views and 20 comments. On social media, attention often passes for credibility.

You text your best friend, who asks her older sister. The sister agrees with the original creator’s claims.

Now you’re really nervous (your sister’s friend has had two boyfriends, after all!). You go back to your mom to say you’re not sure about the plan anymore. You’re scared of what birth control will do to your body. She tries to reassure you that it’s safe, but you can’t stop thinking about the women on TikTok who said it wasn’t.

‘A fertile breeding ground for misinformation’

Even though birth control rumors have circulated for decades, today’s rising mistrust of medical providers and the over-politicization of health, combined with poor digital literacy, have come together to create a fertile breeding ground for misinformation. False claims about infertility and severe mood disorder flourish.

“Data clearly show the deluge of misinformation about reproductive health care, including birth control, on social media,” reads a June 2024 statement from the American College of Obstetricians and Gynecologists, the nation’s top association of OB-GYNs. “This misinformation can cause real harm for patients by encouraging unsafe methods of contraception; by sharing ineffective methods that expose people to unintended pregnancy; or by scaring people away from safe, effective, evidence-based methods of contraception.”

The American Medical Association is likewise sounding the alarm that the rapid spread of misinformation puts lives at risk.

To a certain extent, historic distrust in doctors drives this phenomenon. Physicians have long faced accusations of minimizing women’s medical concerns—by not using anesthesia when inserting intrauterine devices (IUDs), for example, or dismissing reports of pain during pregnancy. This past, which fuels genuine mistrust, is especially prominent in Black and brown communities, where the medical establishment in the 19th and 20th centuries routinely ignored, lied to and exploited patients under the guise of scientific discovery and public health. Any serious efforts to address reproductive health care must acknowledge this legacy, not deny it.

Instead, politicians capitalize on this weakening trust in medicine by amplifying misleading claims. Right-wing commentators like Ben Shapiro and Candace Owens routinely use their platforms to denounce birth control and spread lies about its effectiveness and adverse effects, while claiming they are concerned for women’s health. Some academic researchers and political analysts suggest these are deliberate efforts to dampen opposition should Republicans begin repealing access to birth control using the Comstock Act, an anti-obscenity law from the late 1800s that could stop doctors from mailing contraception or abortion pills. The fewer people believing in the efficacy of birth control, the more compelling their case.

Combatting disinformation together

Too often, efforts to combat misinformation are limited to one-on-one doctor’s office conversations, high school health class (if a school district even offers evidence-based sex education; many don’t), or sporadic debunking posts from reproductive health organizations.

Those of us who believe, as I do, that birth control should be a right for every person who needs it must challenge misinformation and disinformation with the same vigor and coordination as the people and groups spreading it. To meaningfully push back, organizations committed to advancing reproductive health-care access must invest in sweeping digital campaigns—paid, organic, and partnerships—to combat misconceptions and reclaim the narrative around contraception.
I’m not the only one who believes these trends call for swift action to match the scale of the problem.

Power to Decide, an organization working to expand access to reproductive health services, is evolving its long-running hashtag campaign #thxbirthcontrol to meet the moment. What began in 2012 as a campaign on X to influence public perception of birth control has now expanded to other platforms including TikTok, where the group posts short videos that highlight the positive, everyday impacts of contraception.
Combatting stigma with content that’s compelling, relatable, and accurate is essential to combatting misinformation. So is getting that content directly to the people most swayed by misinformation.

At the launch of their new Health Misinformation and Trust initiative, KFF President and CEO Drew Altman explained, “Most Americans have encountered health misinformation, but a large group simply isn’t sure if it’s true or false. Most people fall into this muddled middle place—underscoring the real opportunities we have to counter misinformation but also the risks of inaction.”

While both of these efforts are promising, they cannot be effective in isolation; a coordinated, aligned response is necessary to effectively combat misinformation.

One encouraging approach is Advocates for Youth’s “The Busybodies Club.” This national campaign, which launched before I joined the organization, combines digital education with relational organizing to teach young people how to “spot fake facts, identify misinformation, and challenge misconceptions.” The Busybodies Club is structured to recognize that challenging misinformation requires more than facts—it requires trust, community, and creativity at the interpersonal and systemic levels. The organization’s guide to spot red flags on birth control posts is a great starting point for folks interested in being part of the solution.

And as more organizations join the fight to combat misinformation about birth control, it’s important to acknowledge that hormonal birth control may not be right for everyone. Depending on the method and hormone type, contraceptives may cause headaches, nausea, and mood changes. For people who experience adverse side effects, there are alternatives like the copper IUD, or different hormonal formulations. This kind of honesty is essential to rebuild trust in contraception and for people to truly exercise reproductive autonomy.

Autonomy means choice. Trouble arises, though, when young women use falsehoods to inform their decisions. Misinformation can convince young people, incorrectly, that everyone will have terrible side effects from hormonal birth control or that or that all non-hormonal methods are equally effective. The copper IUD is more than 99 percent effective. Tracking your cycle is not—it fails to prevent pregnancy up to 25 percent of the time.

The current landscape can make it scary for young people to start birth control, and it shouldn’t be. When a girl wants to take charge of her sexual and reproductive health, I believe she should feel empowered, informed, and supported—not frightened. In an era where reproductive autonomy faces relentless attacks online and in legislatures, arming young people with facts isn’t a luxury. It’s a matter of survival.

Disclosure: Shoshana Kaplan is a 2025 graduate fellow at Rewire News Group, focused on sexual health. She is a summer intern at Advocates for Youth, where she receives some funding for her work.

Trump’s DEATH TRAP Leaks… and CHAOS ERUPTS

Florida Cop Bashes Car Window of Black Man, Punches Him in Face in Disturbing Viral Video, and That’s Not All…

https://www.theroot.com/florida-cop-bashes-car-window-of-black-man-punches-him-2000051667?utm_source=theroot_newsletter&utm_medium=email&utm_campaign=%7Bdate_Y-m-d%7D

Dashcam footage of a 22-year-old driver pulled over in a Jacksonville, Fla. traffic stop has left lots of viewers with questions about police and excessive force.

Video of a traffic stop in Jacksonville, Fla., has gone viral. And although the incident occurred nearly six months ago, thousands of outraged viewers are now raising questions about what they believe to be excessive force used on a young Black man.

According to an arrest report obtained by News4JAX, Will McNeil Jr. was pulled over just after 4:00 pm on February 19 because his car “did not have its headlights or tail lights illuminated in inclement weather.” The report reads that McNeil Jr. was not wearing his seat belt and became “verbally combative” with the officer when he was asked to show his identification.

But recently released dash cam video paints a different picture and has many on the internet seeking justice for the 22-year-old driver. The footage shows McNeil Jr. was wearing his seat belt at the time he was pulled over and asked officers to call their supervisor to explain why he was being held when there was no rain or fog at the time he was stopped.

According to First Coast News, officers reported giving McNeil Jr. several warnings that they would break his window if he did not step out of his car. Although those warnings cannot be heard in the video, officers can be seen breaking the driver’s side window and striking McNeil Jr. in the head several times before he was forcibly removed from his car and forced to the ground.

https://x.com/JSOPIO/status/1946975504336294388

https://x.com/FlankyTrades/status/1947259190881161394

 

McNeil Jr. told News4JAX that the incident left him with several injuries, including a concussion.

“I suffered a chipped tooth; my tooth went through my lip, and they slammed me on the ground and on the concrete. I had to get nine stitches. I also had a concussion and now I suffer from short-term memory loss,” he said.

In a statement on X, the Jacksonville Sheriff’s Office acknowledged the incident and said they are conducting their own investigation into the events leading up to the young man’s arrest.

“We are aware of a video circulating on social media showing a traffic stop represented to be from February 19, 2025. We have launched an internal investigation into it and the circumstances surrounding this incident. We hold our officers to the highest standards and are committed to thoroughly determining exactly what occurred,” it reads.

But social media has been flooded with comments from people who believe the proof that the police department is in the wrong is in the video.

“You saw exactly what happened because it was completely recorded. Your own officers stated the reason for his arrest in the video, and he was not resisting. The force used was completely unnecessary. This was a blatant abuse of power. The City of Jacksonville should be ashamed,” wrote someone on X.

Attorney Ben Crump, who will be representing McNeil, told News4JAX that the video evidence is clear that the police were out of line, “It should be obvious to anyone watching this video that William McNeil wasn’t a threat to anyone. He was calmly exercising his constitutional rights, and they beat him for it.”